Newly identified genes, involved in chromatin remodeling, were represented by PBRM1, BAP1, SETD2, KDM5C and KMD6A. Here, in order to specifically identify chromosomal rearrangements spanning PBRM1, BAP1 and KDM5C in the cohort of Polish ccRCC patients, we performed fine mapping of these loci with a cut-off 0.5 MB. Here, PBRM1 is linked to nonpapillary renal cell carcinoma.