UBQLN1 and familial pancreatic carcinoma: Finally, to determine whether miR-675-5p regulates the progression and development of pancreatic cancer via the UBQLN1-ZEB1-mir200 axis, we performed UBQLN1 knock down in Patu8988 cells transfected with miR-675-5p mimics and in SW1990 cells transfected with miR-675-5p inhibitor to detect changes in ZEB1 expression.