Of interest, H19 and miR-675 play different roles in metastasis through the regulation of epithelial to mesenchymal (EMT) and the mesenchymal to epithelial transitions (MET) in different cancers as they can respond to various stress conditions such as reduced p53 and hypoxia, leading to activation of a tumorigenic program of cell survival [9, 10]. The gene discussed is H19; the disease is cancer.