MMP2 and familial pancreatic carcinoma: We also detected that the protein levels of MMP2 and MMP9 were downregulated by miR-675-5p mimics in Patu8988 cells whereas miR-675-5p inhibitors upregulated MMP2 and MMP9 in SW1990 cells, suggesting that miR-675-5p can suppress the migration and invasion of pancreatic cancer.