NRIP is associated with human diseases, high expression levels of IQWD1 (NRIP) in breast cancer tissues are significantly associated with adverse clinical outcomes [5] and NRIP expression is found in six human malignancies (esophageal, colon, breast, ovarian, skin and pancreatic cancers) [6]. The gene discussed is DCAF6; the disease is familial pancreatic carcinoma.