DDB2 and Familial prostate cancer: Furthermore, high expression levels of both NRIP and AR, along with low expression levels of DDB2, compared with all the other seven possible expression patterns of these three proteins (Figure 6C), were found more frequently (odds ratio: 3.52, 95% confidence interval: 1.70-7.29, P < 0.0005) in the same lesions of prostate cancer with the cribriform pattern than in all other types prostate cancer, which were categorized as non-cribriform tumors.