PTEN and hepatocellular carcinoma: Specifically, PTENP1 can modulate PTEN levels by sponging miR21 in ACHN and SN12PM6 renal cancer cells, while exerting its decoy effect by trapping miR17, miR19b and miR20a, which would otherwise target PTEN and several autophagy gene transcripts in Mahlavu HCC cells.