twice daily, CrCl creatinine clearance, CRP C-reactive protein, dTT dilute thrombin time, DVT deep vein thrombosis, eGFR estimated glomerular filtration rate, Hb hemoglobin concentration, ICU intensive care unit, mRS modified rankin scale, NIHSS National Institutes of Health Stroke Scale, NVAF non-valvular atrial fibrillation, PLT platelet, rt-PA recombinant tissue plasminogen activator, TT thrombin time. The gene discussed is PLAT; the disease is stroke disorder.