The resting platelets in whole blood samples obtained from SP MS patients showed 2.3-fold higher CD62P expression (p < 0.05) (Fig. 1a) and 1.5-fold higher level of PAC-1 binding to activated form of GPIIb/IIIa(p < 0.05) (Fig. 2a) in comparison to the control group. The gene discussed is ITGA2B; the disease is myeloid sarcoma.