Membranoproliferative glomerulonephritis (MPGN), types I, II, and III, have been included in this entity.4, -6 The most common form of C3G is MPGN I with predominantly subendothelial deposits, followed by MPGN II, also known as dense deposit disease (DDD).3,7 Patients with DDD have circulating autoantibodies known as C3 nephritic factor. The gene discussed is C3; the disease is dense deposit disease.