According to the cut-off values for identification of overexpressed serum IL-17A and IL-17F, 109 pSS patients were grouped into IL-17F-elevated group (IL-17F ≥ 15.44 pg/mL, n = 43) and IL-17F-normal group (IL-17F < 15.44 pg/mL, n = 66) and IL-17A-elevated group (IL-17A ≥ 13.8 pg/mL, n = 12) and IL-17A-normal group (IL-17A < 13.8 pg/mL, n = 97). The gene discussed is IL17A; the disease is peeling skin syndrome.