We analyzed the influence of CRP on survival according to different subsites: the HR for CRP in tongue cancer DFS 1.785 (95% CI 0.848–3.757); OS 1.535 (95% CI 0.630–3.741); the HR for CRP in buccal cancer, DFS 2.293 (95% CI 1.309–4.017); OS 3.610 (95% CI 1.732–7.526); the HR for CRP in other cancer subsites, DFS 1.577 (95% CI 0.721–3.449), OS 1.252 (95% CI 0.403–3.885). The gene discussed is CRP; the disease is cancer.