Results of quantification indicated that expression of BRAF is induced nearly 2.4 fold with BD, 1.8 fold with 4-OHT and 2.8 fold with combination; expression of Bcl-2/FN1is suppressed around 0.6 fold/0.7 fold with BD, 0.7 fold with 4-OHT and 0.4 fold with combination; expression of p21 is induced nearly 2.9 fold with BD and 2.7 fold with combination (Fig. 3b). This evidence concerns the gene BCL2 and Behcet disease.