RECK and cancer: As shown in Figure 5A, the Cancer Genome Atlas (TCGA) data of RECK mRNA levels in 548 GBM tumor tissues assessed by Affymetrix U133A arrays revealed that RECK mRNA levels ranged from 4.06 to 7.25 with more than 95% samples below median expression level 6.0, so the expression of RECK mRNA in the majority of the GBM tumor tissues was low.