PPARγ, expressed in the adipose tissue [4,5], regulates adipocyte differentiation and insulin sensitization, playing a key role in the regulation of lipid metabolism in mature adipocytes and macrophages [6], with a direct impact on type 2 diabetes, dyslipidemia, atherosclerosis, and cardiovascular diseases [7,8]. The gene discussed is PPARG; the disease is type 2 diabetes mellitus.