RASSF1 and melanoma: According to the meta-analysis, we found that the frequency of RASSF1A gene promoter methylation in melanoma was: OR = 12.67, 95% CI: 6.16∼26.05, z = 6.90, P<0.0001 by a fixed effects model and OR = 9.25, 95% CI: 4.37∼19.54, z = 5.82, P<0.0001 by a random effects model without evidence of heterogeneity (tau2 = 0.00; H = 1 [1; 1.55]; I2 = 0% [0%; 58.6%], P = 0.5158).