ADAMTS4 and intervertebral disk degenerative disorder: In this study NP cells of disc degeneration grade III (Table 1 & Fig 1) transduced with the recombinant scAAV6 vectors AAV6-ADAMTS4 or AAV6-Ctrl showed high and similar long-term transduction efficiencies in the course of 48 days (p ≥ 0.648).