As shown in Table 1, with the progression of the disease stage of schistosomiasis japonica, the indicators of liver function in patients, for example, ALT, AST, TB, DB, GGT, GLB, ALP, and of liver fibrosis, for example, HA, PCIII, IV-C, and LN, showed an increasing trend; this was more serious in advanced schistosomiasis. This evidence concerns the gene GPT and Hepatic fibrosis.