For example in Sharabi et al's study[44] using B16-OVA melanoma cells and 4T1-HA breast carcinoma cells, it was observed that radiation could enhance tumor-specific antigen-MHC complexes, increase T-cell infiltration into tumor cells, and upregulate antigen cross-presentation in the draining lymph nodes. The gene discussed is HLA-C; the disease is neoplasm.