We used database interrogation of the microarray-based Neuroblastoma Database [12] to identify and select a limited number of potential [Ca2+]i signaling-related molecules that might be of relevance in neuroblastoma, including inositol triphosphate receptors I and III (ITPR1, ITPR3), ryanodine receptors 1 and 3 (RYR1, RYR3), and the S100 calcium-binding protein A6 (S100A6). This evidence concerns the gene RYR3 and neuroblastoma.