ITPR1 and neuroblastoma: Expression of ITPR1 and ITPR3 transcripts was as well deregulated in SH-SY5Y neuroblastoma cells upon treatment with CDDP or TOPO (Figure 3A and 3B) this effect was also observed for both treatments in IMR-32 cells (Figure 3C and Supplementary Figure 3) and for CDDP treatment in NLF cells (Supplementary Figure 3).