Statistical difference of the expression of HPGD protein in breast cancer tissues was detected between normal weight group and obese group (χ2 = 19.079, p < 0.001), between overweight group and obese group (χ2 = 5.761, p = 0.016), and between normal weight group and overweight group (χ2 = 4.204, p = 0.04) (Table 2B). The gene discussed is HPGD; the disease is breast cancer.