ALCAM and melanoma: On the other hand, the expressionof cell-cell adhesion receptors of the immunoglobulin superfamily of cell adhesionmolecules (CAMs) is higher in melanoma cells than in melanocytes5.ALCAM (CD 166) and MCAM (CD 146) were already described as intercellular adhesionmolecules in melanoma cells and their expression correlates with enhanced melanomadevelopment, metastatic properties and tumour progression (ALCAM39, 40; MCAM41, 42).