For example, mNT was implicated in diabetes, obesity, and cancer1, 16, 17, and NAF-1 was implicated in BCL-2-Beclin-1-BIK-dependent autophagy and BCL-2-dependent apoptosis, as well as in neurodegenerative diseases, skeletal muscle maintenance, cancer, and aging1, 10, 11, 12, 13, 14, 15, 17, 18, 21, 22, 23. This evidence concerns the gene BCL2 and obesity disorder.