SEH1L and Autoimmunity: For example, in the largest subunit of the NPC, 3 out of 9 putative complex members of the Nup107-160 sub-complex, i.e., MOS3/Nup96, Nup160, and Seh1, were found to be essential for the basal resistance and snc1 activated autoimmunity in Arabidopsis (Du et al. 2009; Ratner et al. 2007).