Interestingly, key PD-associated genes, α-synuclein (SNCA), PARK2, deglycase (DJ-1), leucine-rich repeat kinase 2 (LRRK2), and glucocerebrosidase (GBA), are all expressed in immune cells, implying their potential role in immunity (reviewed in ref. [2]). The gene discussed is GBA1; the disease is Parkinson disease.