Here, we measured the IL-25, IL-33, and TSLP levels in a relatively large cohort of patients with IPF and other interstitial lung diseases, including non-specific interstitial pneumonia (NSIP), hypersensitivity pneumonitis (HP), and sarcoidosis in order to evaluate the significance of these cytokines on clinical outcomes of IPF. This evidence concerns the gene IL33 and interstitial lung disease.