As recorded, the first line of antioxidant defense represented by total SOD activity in POAG patients (17.48 NU/ml; SD: 3,12 95% CI: 16,3–18,6) was decreased as compared with healthy controls (20,43 NU/ml; SD: 4,03 95% CI: 18,80–22,06) - Table 2. Here, SOD1 is linked to open-angle glaucoma.