EGFR and metastatic malignant neoplasm in the lymph nodes: As shown in Figure 2, high EGFR expression was found to be significantly related with lymph node metastasis (Figure 2A, present vs absent, OR=2.20, 95% CI: 1.63-2.96, Z=5.17, P=0.001), tumor differentiation (Figure 2B, poor vs well/moderate, OR=1.96, 95%CI: 1.14-3.34, Z=2.43, P=0.015), and tumor stage (Figure 2C, I-II vs III-IV, OR=2.13, 95% CI: 1.35-3.36, Z=3.25, P=0.001).