LOXL2 and neoplasm: The effects on tumor growth observed in our study may also be in part due to the effect of LOXL2 inhibition on reduced angiogenesis as well as CAF-activation, something which was not reported in the 2013 study, determining whether LOXL2 modulation of CAF activation and angiogenesis are mutually exclusive in this context is beyond the scope of this study.