IGHE and asthma: We observed stronger associations between paternal total IgE and asthma with hayfever in both sons and daughters (RRR = 2.31 (95% CI 1.72, 3.12) and 1.99 (95% CI 1.40, 2.85), respectively), as compared to maternal total IgE and asthma with hayfever in her sons and daughters (RRR = 1.31 (95% CI 1.04, 1.66) and 1.37 (95% CI 1.07, 1.77), respectively).