A similar difference was observed for any positive specific IgE measured before conception compared to after birth of the child [aRRR = 3.08 (2.13, 4.45) and aRRR = 1.83 (1.45, 2.31), respectively (Table 2)], as well as for increasing asthma score and total IgE (Table 2 and Fig. 2). The gene discussed is IGHE; the disease is asthma.