HLA-DQA1 and multiple sclerosis: For mosquito bite size, the index SNP (rs3134995; P = 1.9 × 10−24) is in LD (r2 = 0.51) with the nonsynonymous variant rs9260 (M230V) in HLA-DQA1, plus variants that are eQTLs for eight HLA genes (Table 5) and the variant rs3129720 previously identified as a risk factor for multiple sclerosis (19), and hypothyroidism (20).