IGHA2 and Alzheimer disease: Cellular components such as the IgA immunoglobulin complex (IGHA1, IGHA2, and IGJ) endoplasmic reticulum membrane (DHRS7C, RHO), vesicle lumen (APOB), and mitochondrial segments (mainly governed by Bcl3) were clearly upregulated in AD which highlight the involvement of mitochondria, endoplasmic reticulum, and vesicle formation in AD.