NPPB and chronic obstructive pulmonary disease: Independent predictors of cardiac events or death included 6-minute walk distance (p<0.001), chronic obstructive pulmonary disease (p = 0.010), NT-proBNP (p<0.001), E/A ratio (p = 0.003), RV dysfunction (p = 0.011) and systolic PAP (p<0.001).