STXBP6 and lung adenocarcinoma: In conclusion, our results indicate that the pathogenesis of lung adenocarcinoma may result from epigenetically regulated expression levels of STXBP6. Before this biomarker can be translated into clinical utility, further studies using larger sample sizes will help to reveal the importance of STXBP6 as novel potential biomarker for the prognosis of lung adenocarcinoma56.