ALB and diabetic kidney disease: Microalbuminuria was defined as albumin excretion rate (AER) 30 to 299 mg/24 h “incipient nephropathy,” progressed steadily to macroalbuminuria with AER ≥300 mg/24 h “diabetic nephropathy.” Microalbuminuric patients commonly noted to have higher GFR “hyperfiltration,” while macroalbuminuric patients showed rapid GFR loss leading steadily to ESKD.