Because two of the five peptides inthe lytic peptide pool were restricted by HLA-A*02 (Table2) we wished to ensure that the decreased CD8+ T-cellresponse to the lytic peptide pool was not due to the lower frequency of thisallele in patients with MS.19, 31 We therefore measured the response to thelytic peptide pool in HLA-A*02+ subjects. Here, HLA-A is linked to myeloid sarcoma.