Enteropathy is one of the major clinical symptoms of several primary immunodeficiencies (PIDs) (1), such as immunodysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome, and chronic granulomatous disease (CGD), as well as the IL-10/IL-10-receptor (2), CD25 (3), and Stat5b deficiency (4). This evidence concerns the gene IL10 and Abnormal intestine morphology.