KCNN4 and autoimmune disease: KCa3.1 channel functions have been linked to abnormal cell proliferation, pathological tissue remodeling and fibrosis of a variety of organs, chronic inflammation, and autoimmune diseases (Wulff and Zhorov, 2008; Roach et al., 2013; Wulff and Köhler, 2013; Feske et al., 2015; Huang et al., 2015; Köhler et al., 2016).