At this point, we would like to remind the reader that KCa3.1 functions in disease states have been so far related to pro-proliferative and -inflammatory processes and pathological organ remodeling such as kidney and lung fibrosis (Wulff and Zhorov, 2008; Roach et al., 2013; Wulff and Köhler, 2013; Feske et al., 2015; Huang et al., 2015; Köhler et al., 2016). The gene discussed is KCNN4; the disease is pulmonary fibrosis.