Considering the reported beneficial effects of dietary supplementation of α-LA and α-LA-rich plant oils on autoimmune diseases and chronic inflammation such as multiple sclerosis, rheumatoid arthritis, psoriasis, chronic inflammatory bowel disease, or atopic dermatitis (Macfarlane et al., 2011; Wergeland et al., 2012; Yates et al., 2014) we were curious to learn whether α-LA-rich plant oils were also capable of inhibiting KCa3.1. Here, KCNN4 is linked to autoimmune disease.