CHRNA7 and viral myocarditis: Recently, we have also demonstrated that cholinergic stimulation with α7nAChR agonist nicotine had a protective effects in murine viral myocarditis, and selective α7nAchR antagonist methyllycaconitine had a deleterious effects in the same setting (Zheng et al., 2014; Ge et al., 2015, 2016).