Another miRNA, miRNA let-7b, has been shown to be upregulated in prostatic TAMs (established by the incubation of human blood monocytes with PCa prostate cancer cell conditioned medium) and modulates IL-12, IL-23, IL-10, and TNF-α and promotes mobility of PCa cells and proangiogenesis of PCa-conditioned TAMs [134]. Here, TNF is linked to posterior cortical atrophy.