TFG and hereditary motor and sensory neuropathy, Okinawa type: A heterozygous mutation (P285L) in Tropomyosin-receptor kinase Fused Gene (TFG) was identified as the gene responsible for HMSN-P, and the pathological hallmark of HMSN-P is the formation of cytosolic inclusions of TFG protein in spinal MNs [5].