Although defective proteins that are rapidly recycled from the autolysosome in the autophagy process may contribute to cell migration in some cancers53, the role of the extent of autophagy in cellular EMT during cancer progression remains unclear, and analysis of BNIP3-dependent mitophagy based on AhR protein levels in NSCLC is warranted. This evidence concerns the gene BNIP3 and non-small cell lung carcinoma.