PTHLH and neoplasm: With median follow-up of 97 months (range 5–243), PTHrP staining in primary tumour was found to correlate with the development of BM with a HR of 7.104 (95% CI, 1.782–48.110; p = 0.0037), along with having a T4 tumour, in a multivariate logistic regression analysis [77].