KRT7 and neoplasm: Electrochemistry luminescence immunity analysis showed that levels of CA19-9 and AFP were significantly increased in the culture supernatant of TJ-GBC2 cells; that CK7, CK8, CK19 and E-cadherin proteins were positively expressed in the xenograft of nude mice, with negative expression of mesenchymal marker vimentin, which is in accord with the results of primary tumor.