For example, using RNA-seq to analyze prostate cancer tissues, the landscape of lncRNAs in prostate cancer has been recently defined and notably includes prostate cancer functional lncRNAs, such as PCA118 and SChLAP1.19 In the case of ESCC, Ma et al.20 has applied transcriptome sequencing to ESCC tissues from three patients and adjacent non-tumor tissues. This evidence concerns the gene SCHLAP1 and Familial prostate cancer.