BIRC3 and neoplasm: Supporting amplification of this region, analysis of our microarray data revealed much higher expression levels of multiple genes (for example, Dync2h1, Mmp3, Mmp10, Birc2, Birc3, Yap1) from this region in almost all profiled Type 1 tumours (for example, E2, E4, E5, E9, TB208, TB209, TB239-2), but not in the Type 2 tumour E8 (Fig. 5b, top).