IFNG and neoplasm: Re-stimulation of the isolated TILs with DCs loaded with B16-F10 tumour lysates demonstrated an increase in IFNγ production by intracellular cytokine staining suggestive of tumour-specific immunity, which was most pronounced in combination therapy groups, although there was no significant difference between NDV-WT and NDV-ICOSL (Fig. 5j; Supplementary Fig. 8).