RETN and Insulin resistance: The CRY/TYW3 locus has previously been associated with circulating resistin levels, a hormone associated with insulin resistance, inflammation, and risk of type 2 diabetes and cardiovascular disease.60SLC44A5 encodes a solute carrier protein and is important for metabolism of lipids and lipoproteins, and has been associated with birth weight in cattle.61PAFAH1B1 encodes a subunit of an enzyme that has important roles in brain development and spermatogenesis.