INS and metabolic syndrome: All of the metabolic syndrome components were similar in the chemotherapy group (normal group vs overweight/obese group), except for waist circumference (p < 0.0001) and other metabolic variables such as insulin level (16.3 μU/mL vs 24.9 μU/mL, p = 0.010), HOMA-IR index (3.6 vs 5.5, p = 0.033), leptin level (4.4 ng/mL vs 18.2 ng/mL, p < 0.0001), leptin-to-adiponectin ratio (0.27 vs 0.98, p < 0.0001), and fat mass percentage (23.4 vs 38.3, p < 0.001).