CRP and familial pancreatic carcinoma: Fearon and co-workers described a population consisting of 170 advanced pancreatic cancer cachectic patients using Karnofsky Performance Score, grip strength, dietary intake, quality-of-life assessment with EuroQol EQ-5D and QLQ-C30, CRP, and CA19-9, but they were mostly concentrated on evaluation whether a 3-factor profile incorporating weight loss, low food intake, and systemic inflammation might relate better to a patient’s overall prognosis than will weight loss alone [14].