FASN and infection: While siRNA mediated knock down of FASN had a larger effect on both virus production and percentage infection that treatment with orlistat, there is a less clear path to application in the treatment of DENV patients with siRNA based therapies than for the already licensed orlistat, and therefore evaluation of the effects of knock down of FASN by siRNA on DENV infection were less comprehensive than the studies undertaken with orlistat.