Notable exceptions to this trend were DGAT1, which in both cell lines showed a reduction in gene transcription at 24 h in infected cells (Figs. 2 and 3), and a significant increase in gene transcription by day 3 post-infection as compared to mock infected cells, as well as the lipogenesis genes FASN and SREBP1c in HEK293T/17 cells and the lipolysis gene ATGL in HepG2 cells (Fig. 2 and 3). The gene discussed is PNPLA2; the disease is infection.