The lack of a significant relationship between 25(OH)D and albumin in IBS is similar to the findings of a study on albumin and 25(OH)D in inflammatory bowel disease [37]; and the absence of a significant relationship between ALT and 25(OH)D in IBS is also consistent with a report that characterized the relationship between vitamin D and liver enzymes in adult patients with liver disease[38]. This evidence concerns the gene GPT and irritable bowel syndrome.