NPPB and Sepsis: In this regard, there have been multiple biomarkers used in the diagnosis and stratification of sepsis, including interleukins, cytokines, C-reactive protein, procalcitonin, lipopolysaccharide binding protein, coagulation factors, atrial natriuretic peptide and brain natriuretic peptide (ANP and BNP respectively), among many others [3,4].